Run the following command in the EM Shell. It cant be done in the GUI
Get-ReceiveConnector "Anonymous Relay" | Add-ADPermission -User "NT AUTHORITY\ANONYMOUS LOGON" -ExtendedRights "Ms-Exch-SMTP-Accept-Any-Recipient"
If you have a server where the IMA service wont start try the following command on it.
dsmaint recreatelhc
If you see the error in the event log with an ID of 123 and source ExchangeStoreDB :-
At ’3/16/2012 11:42:51 AM’ the Microsoft Exchange Information Store Database ‘DATABASENAME’ copy on this server experienced a corrupted search catalog. Consult the event log on the server for other “ExchangeStoreDb” and “MSExchange Search Indexer” events for more specific information about the failure. Reseeding the catalog is recommended via the ‘Update-MailboxDatabaseCopy’ task.
Then you need to reseed the catalogs on the backup server.
Carry out the following steps.
1) Suspend the Database on the backup server. Right click, suspend.
2) Open Exchange Management Shell, Run the command.
Update-MailboxDatabaseCopy –Identity DATABASENAME\BACKUPSERVER –SourceServer MOUNTEDSERVER
3) This will then copy across the catalogs
4) Unsuspend it
Source : Technet
Microsoft Exchange Server 2003 6.5.6944
Microsoft Exchange Server 2003 SP1 6.5.7226
Microsoft Exchange Server 2003 SP2 6.5.7638
Microsoft Exchange Server 2003 post-SP2 6.5.7653.33
Microsoft Exchange Server 2003 post-SP2 6.5.7654.4
Microsoft Exchange Server 2007 8.0.685.24 or 8.0.685.25
Microsoft Exchange Server 2007 SP1 8.1.0240.006
Microsoft Exchange Server 2007 SP2 8.2.0176.002
Microsoft Exchange Server 2007 SP3 8.3.0083.006
Microsoft Exchange Server 2010 14.00.0639.021
Microsoft Exchange Server 2010 SP1 14.01.0218.015
Run the following command in the EMC to list all mailboxes who have delegates on them.
Get-Mailbox -resultsize unlimited | Where {$_.GrantSendOnBehalfTo -ne $null} | select Name, @{Name='GrantSendOnBehalfTo';Expression={[string]::join(";", ($_.GrantSendOnBehalfTo))}} | Export-CSV C:\SendOnBehalfTo.csv -noTypeInformation
If Microsoft Access 2003 keeps saying preparing to install everytime you load it just import this file into your registry.
Job done 
Most of the times its located in :
C:\Windows\SYSMSI\SSEE\MSSQL.2005\MSSQL\Data
If it needs shrinking do the following :-
Backup the database using SQL Management. Connect to the instance using
\\.\pipe\MSSQL$MICROSOFT##SSEE\sql\query
as the server name.
Once backed up right click on the Database Sharepoint Config and click new query.
Execute each of the following querys in turn
BACKUP LOG [Sharepoint_Config_blahblahblah] TO DISK='D:\temp\configLogBackup.bak'
GO
BACKUP LOG [Sharepoint_Config_blahblahblah] WITH TRUNCATE_ONLY
USE [Sharepoint_Config_blahblahblah]
GO
DBCC SHRINKFILE (N'Sharepoint_Config_blahblahblah_log' , 50)
GO